Cognitive Performance · Focus · Ingredient Monograph

Stadice®

Mangifera indica extract · standardised to mangiferin

Stadice®: mango extract standardised to mangiferin. Significant gains in attention, memory and mental speed in 7 days (n=60, double-blind). From Biontera.

Stadice®

Stadice® is a proprietary cognitive-health ingredient derived from mango (Mangifera indica) extract, standardised to mangiferin ; developed for the rising "nootropic" category of e-sports, academic-performance and professional-focus formulations.

In a randomised, double-blind, placebo-controlled study of 60 healthy volunteers who regularly play digital games, 300 mg/day of Stadice® produced significant improvements versus placebo in mental speed, attention, working memory, response inhibition, and verbal learning and memory ; in just 7 days. The NIMHANS Neuropsychological Battery and auditory-verbal learning tests were used; favourable findings were also recorded in psychological stress response.[1]

E-sports and gamer performance formulations
Academic focus & exam-support products
Professional cognitive performance (high-tempo professionals, drivers)
Age-related cognitive-support combinations
Caffeine-free nootropic positioning — shots, capsules, gummies
n=60
Randomised, double-blind, placebo-controlled
7days
Onset — one-week protocol
Clinical and Technical Evidence

Mangiferin — a xanthone glycoside — is a polyphenol whose neuroprotective and antioxidant mechanisms have been extensively studied at the experimental level. The Stadice® clinical programme carries this experimental base into measurable cognitive endpoints in healthy adults.

Primary assessment used the cognitive-ability tests of the NIMHANS battery; management of nervousness, irritability and mood swings plus cortisol levels were tracked as secondary measures. No safety concerns were reported. The one-week onset enables formulation design for acute-use scenarios (exam periods, tournaments, intensive projects).

Clinical · CognitivePublished manuscript

Cognitive efficacy study in healthy adults

Significant gains versus placebo across multiple cognitive domains measured by the NIMHANS battery and AVLT; positive stress-response findings, no safety issues. Randomised, double-blind, placebo-controlled · n = 60 (regular digital gamers) · 300 mg/day · 7 days

Significant improvement
Mental speed & attention
Significant improvement
Working memory
Significant improvement
Verbal learning & memory
Identity and Technical Dossier

Every shipment can be delivered with a 12-item technical documentation file on request:

Lot-based Certificate of Analysis (CoA)
GMP certificate
Product specification
Analytical methods
MSDS safety data sheet
TDS technical data sheet
Stability and shelf-life data
Manufacturing flow chart
Certificate of origin
Allergen and GMO-free statement
BSE/TSE statement
Halal and Kosher certificates (on request)
Frequently Asked Questions
How quickly does Stadice® act? +

The clinical protocol was 7 days; at its end, a significant difference versus placebo was measured across multiple cognitive tests ; an unusually short onset for the category.

Which tests were used? +

Cognitive-ability tests of the NIMHANS Neuropsychological Battery and auditory-verbal learning tests (AVLT); plus stress, anxiety, mood and cortisol measurements.

Does it contain caffeine? +

No. Stadice® is a stimulant-free, mangiferin-based botanical extract, suited to caffeine-free nootropic positioning.

Which formats can it be used in? +

Capsules, tablets, gummies and shots; the 300 mg daily dose fits in a single unit.

References
  1. [1]Stadice®, a proprietary herbal preparation standardized to mangiferin: randomized, double-blind, placebo-controlled clinical study on cognitive wellness in healthy subjects, n=60, 300 mg/day, 7 days.Published clinical manuscript
First Step

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